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CBGA Strongly Inhibits Inflammation

February 19, 2019

Graphical abstract. Credit: Function (2022). DOI: 10.1093/function/zqac033

Several minor cannabinoids contained in the cannabis plant “strongly inhibit” the activation of human immune cells that lead to chronic inflammation, according to physiologists at The Queen’s Medical Center and University of Hawaii. The study also revealed the strongest inhibitory cannabinoid, cannabigerolic acid, disrupts a key mechanism that allows calcium ions to enter and activate immune cells. As a result, cannabigerolic acid suppresses the spread of inflammatory signals.

Chronic inflammation is a biological process in which inflamed tissues release messenger molecules called cytokines. These . . .

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